cannabidiol wax crumble

Gain A Real Understanding Of CBD

For anyone interested in the benefits of CBD, this guide will give you fact-based answers to your questions.

How can CBD help you?

The medical studies selected for this guide are published by highly reputable organizations.  Collectively, they show CBD has a consistent and positive impact on individuals who experience a broad array of conditions including anxiety and physical pain.

In this guide, you’ll gain an understanding of exactly why CBD has such wide-ranging effects as well as:

  • learn how CBD may benefit you
  • learn the mechanics of how CBD affects mood, emotions, and health
  • learn techniques to boost CBD effects
  • learn how to recognize possible adverse effects

All the answers to your CBD questions are here so let’s get started.

If you don’t find an answer in this guide to a question you have, leave us a comment below. We’ll search the published studies to see if an answer exists and get back to you.

cbd oil dropper

What Is CBD?


CBD Definition: CBD (cannabidiol) is a non-intoxicating organic compound naturally produced by the cannabis plant (including hemp plants). 

CBD very closely mimics in its molecular structure chemicals your body already makes called endocannabinoids. 

cbd pain relief graphic

Endocannabinoids help to maintain critical regulatory systems as part of your central nervous system.  Endocannabinoids are signaling agents that operate within your central nervous system to help regulate emotional, cognitive, and physiological systems.

In your body, CBD imitates one or more of the endocannabinoids your body normally generates.  When you take CBD, your body recognizes this external cannabinoid (CBD) as if it had been produced by your body. Your body responds to CBD as if it were an endogenously produced (meaning produced within your body) signaling agent or neurotransmitter.

cannabis sativa leaf

CBD is one of 113 cannabinoid compounds made by the cannabis plant. (2)

Many of the 113 cannabinoids produced by hemp and cannabis plants have beneficial impacts on our central nervous system.  Unfortunately, thorough medical research into their effects hasn’t been possible until recently due to prohibition.

CBD properties


Unlike THC (the active ingredient in marijuana), CBD doesn’t have a euphoric “high.” (3)

CBD and THC are entirely different compounds with separate chemical structures and distinct effects on your central nervous system.

vegetative hemp plant

When CBD and THC are taken together, CBD “down-regulates” or counteracts some of the euphoric effects of THC.

Many medical studies suggest that taking THC and CBD together increases the benefits of both compounds.  It is usually suggested to consume a ratio of THC to CBD anywhere from 1 to 1 (THC to CBD) all the way up to 1 to 10 (THC to CBD).

Unlike CBD, THC is known to cause anxiety. If you are taking THC for therapeutic reasons, it is frequently recommended to take CBD at the same time.  Medical studies have shown that CBD has anxiolytic effects (anti-anxiety effects) especially for anxiety caused by THC. (4)

cbd thc differences

When CBD and THC are taken together, CBD down-regulates or counteracts some of the adverse effects of THC. tell a friend

two people face to face showing the effects of CBD skincare

CBD Health Benefits

There has been a lot of business and media hype about CBD in the last few years.  In that context, it is only natural to be skeptical of many of the claims you have have heard about CBD.

While outlandish claims about CBD may even be the norm on social media, CBD is in fact a promising medicinal compound.

CBD has multitargeted effects on the nervous system and circulatory system and has few known adverse effects according to the most recent medical literature.

cannabidiol mental health

CBD is frequently taken to help with:

  • anxiety
  • stress
  • depression
  • relaxation
  • inflammation
  • appetite control
  • pain relief
  • skincare

cbd oil dropper for skincare

Though it has been known for decades that CBD was a promising compound with potentially wide-ranging benefits, the prohibition against the farming of hemp plants kept CBD out of the hands of scientists and medical professionals.  All of that changed in 2018.

CBD made from low THC cannabis (hemp) was legalized federally in the 2018 Farm Bill. (5)

cannabidiol legal status

Legalization freed up farmers, researchers, and grant money to study the medical benefits of CBD.

Since legalization, the NIH, universities, and scientific journals have published numerous studies on the medicinal benefits of CBD.

There is even a 2019 NIH initiative launched specifically to study CBD and its potential uses.

This initiative will also study minor cannabinoids (like CBG) and beneficial cannabis compounds called terpenes.

cbd pain treatment

While knowledge about the benefits of CBD is going mainstream, the question still persists: “How exactly does CBD work?”

Let’s find out.


How does CBD work?

How can one organic compound made by a plant have such wide-ranging effects?

hemp flower with cannabinoid crystals visible

The short answer: CBD mimics a key signaling agent (or neurotransmitter) that your body uses to keep itself in good operational balance. That chemical is called anandamide and your body makes it naturally. Your body uses anandamide as a kind of messaging chemical to send “up-regulation” and “down-regulation” signals to different regulatory subsystems.  So when you take CBD, you are affecting how your body is messaging or signaling its regulatory subsystems.  These subsystems have significant effects on mood, health, and pain. (6) (7)

The overall signaling system of which anandamide is a part and CBD affects is called your endocannabinoid system (ECS).  It’s a critical system that was—amazingly—only discovered by the medical research community in 1992.

Notice the ‘cannabinoid’ part of the name endo-cannabinoid? More on that later but take note of it now.

balance pineapple at the ocean (decorative)

The endocannabinoid system is part of your central nervous system.  It exists in your brain, spine, and throughout your body.(8)


cannabidiol mental health


It has vast abilities to affect your mood and health.

cannabidiol ECS benefit

So when you take CBD and subsequently feel better, it is not the CBD that is directly making you feel better.  Instead, the CBD you’re taking is activating different regulatory systems and signaling that they should “turn on.”  Those systems then get to work and release other types of natural compounds within your nervous system. All this occurs with the goal of restoring balance to your overall functioning.

That’s the key to how CBD works.

It has important effects on your central nervous system which activate regulatory systems in your body to restore balance or homeostasis.

Not so complicated, right?

image of a lizard looking for dinner

CBD is all about boosting your body’s own regulatory systems. That’s why it works.

More on your endo-cannabinoids regulatory system later

First, what’s the exact legal status of CBD in the U.S.?




CBD Benefits For Addicts

CBD is not addictive and not habit-forming.

In fact, studies show CBD may decrease withdrawal symptoms and cravings in opioid, alcohol, and tobacco addicts. (10)

cannabidiol withdrawal relapse effects



cannabis sativa plant high in cbg (cannabigerol)

CBD vs. CBG vs. CBN

Hemp plants contain over 113 cannabinoids.  Many of those lesser-known cannabinoids have health benefits that have yet to be described by medical science.

It’s likely that CBD (or any of the better-known cannabinoids) is used as a sort of shorthand for a variety of helpful effects that actually originate with lesser-known cannabinoids.

That’s why broad-spectrum and full-spectrum CBD products are said to work better than CBD isolate.

young woman with colored hair that connotes autism spectrum

Broad-spectrum CBD products retain in the final product most of the cannabinoid profile to be found in a specific strain.

Some of the cannabinoids found in broad-spectrum CBD products and likely have health or mood benefits are CBG and CBN.

Full-spectrum CBD oil delivers the complete cannabinoid profile of a hemp strain.

Full-spectrum products are your best bet for getting the most benefit from CBD.

CBD is also available in tincture form, isolate and wax concentrate (including live rosins).

cbd live rosin

CBD tinctures and isolates are usually consumed orally.

On the other hand, CBD wax and rosins can be dabbed or added to a food recipe.

Check out this study: Dabbing is 394% more effective than smoking a CBD joint with no combustion.  Wow!

cannabidiol rosin extract

While CBD is the most well known, CBG and CBN are gett a lot of research attention in 2020.

Recent studies have shown CBG has pain and inflammation relieving properties potentially useful for difficult to treat pain and neuropathic pain. (11)

cannabigerol inflammation benefits

Beyond treating pain, CBG’s inflammation benefits even appear to slow brain aging.

According to the 2018 study below, CBG may have benefits for neurodegenerative diseases like dementia too. (12)

cannabigerol anti-inflammatory properties

In this 2019 study, CBN (cannabinol) is shown to be a strong sedative that helps with anxiety and insomnia. (13)

cannabinol insomnia anxiety


Additionally, NIH research shows CBN is a promising candidate for treating PTSD. (14)

CBN PTSD study

As shown earlier in this guide, cannabinoids work by effecting a regulatory system called the endocannabinoid system (ECS).

In the next section, you’ll find out some surprising facts about your ECS and how it can affect your emotional and physical health.

You’ll also learn how you can put CBD to work to feel better and be healthier.


car engine metaphor for how CBD words

Why CBD Works


CBD works because it mimics a signaling compound in your endocannabinoid system called anandamide.

The Endocannabinoid System (ECS) is an important part of your nervous system.

The ECS is found in your brain, spine, and throughout your body. (15)

The scope of the ECS borders on the ridiculous.

Your ECS regulates:

  • appetite
  • mood (anxiety and depression)
  • stress reaction
  • sleep
  • pain
  • memory
  • fertility
  • aggression
  • confidence
  • fear
  • and much more

Your ECS constantly performs critical wellness functions to keep your body chemically balanced.

It also has a significant role in emotional stability and happiness. (16)

The ECS was discovered in 1992.

Some claims are made that only 5% of doctors received training on the ECS while in medical school.

So, it’s up to you to educate yourself about CBD and your ECS.

Knowing about your ECS is an opportunity. By educating yourself about cannabinoids and the ECS,  you can have more control over your own health choices and how you’re going to feel on a day to day basis.

female hands making notes

So…how do you want to influence your ECS with CBD?

How are you going to adjust your CBD regimen to change the way you feel?



Video: ECS Explained


I love this video.

This is Dr. Ruth Ross’s superb TED talk explaining the endocannabinoid system.

dr. Ruth ross in a laboratory


Dr. Ross is an expert in the field of cannabinoids and the endocannabinoid system.

She is also an entertaining speaker. Enjoy.


CBD For Anxiety


Clinical definition of anxiety: hypersensitivity to stimulation in a nonthreatening environment.

That medical definition essentially means a person with anxiety is someone who reacts to unthreatening situations as if a threat were present. Additionally, people with anxiety become hypervigilant—always on guard feeling like a threat could appear at any time.

For a person with anxiety, a threat may be a physical threat or a social threat or an emotional threat.

I am a person who has struggled with anxiety my whole life.  Anxiety is the reason I first started researching and taking cannabinoids.

Anxiety Graphic

What I’ve found in my personal experience is CBD helps shift the way your body responds to anxiety.

This experience is backed up by the medical studies below.

CBD works by signaling your endocannabinoid system to down-regulate anxious feelings, especially when they are spiraling out of control. (17)

Though no single study has been definitive, CBD is consistently reported as having an anxiolytic effect across a broad range of medical studies.

Anxiolytic is a scientific term for a substance that produces anxiety-relieving or anti-anxiety effects.

Your body has systems that are supposed to keep your thinking and emotions within certain normal ranges.  After all, you’re supposed to feel “normal” most of the time.

building with mural asking how are you feeling

So, another way to look at anxiety is there are systems in your body that are supposed to keep you feeling normal and they aren’t doing their job.

Those systems are not maintaining your chemical balance properly. In turn, that chemical imbalance then causes you to respond to non-threatening situations with anxious thinking and feelings.

When you choose to take CBD, your conscious brain is asserting control and effectively saying, “Hey, something isn’t right about how I’m feeling right now. I need to fix this.”

pilot flying aircraft at night

As the CBD you decided to take gets absorbed into your body, your endocannabinoid system relates to it as if it were a naturally occurring substance called anandamide. Anandamide is a naturally-occurring neurotransmitter in humans and CBD mimics it perfectly.  Anandamide is used by your endocannabinoid system to relay control signals to other more specialized regulatory subsystems throughout your body.

After being signaled by the presence of higher levels of anandamide or CBD in your body to “turn on,” those regulatory subsystems then get to work creating different chemicals that restore your feeling of equilibrium or normalcy.

This return to equilibrium can feel like being relaxed or even uplifted.

Studies show that CBD may even make you feel more confident. (18)



Anxiety is one of the most common reasons people take cannabinoids.



The 2015 study below reports CBD has results even in cases of severe anxiety disorders. (19)




CBD For Depression


CBD may benefit depression but the results for depression are less clear than they are for anxiety and pain relief. (20)

According to a 2014 study, CBD affects the serotonin and dopamine uptake and may have antidepressant-like effects.



Serotonin and dopamine are the chemicals in the brain that many pharmaceuticals act upon to treat clinical depression.

While it is still not known if CBD can treat depression, taking CBD does have very few side effects.  Side effects are one of the main reasons patients stop taking pharmaceutical antidepressant drugs like Prozac.

Check out this guide to CBD for depression to see some of the latest medical studies investigating CBD’s benefits for depression symptoms.


The 2019 study below found that CBD induces rapid and sustained antidepressant-like effects by affecting nervous system signaling in the brain. (21)



While pharmaceutical drugs take up to 6 weeks before having a positive effect, some general practitioner doctors claim CBD starts to have a positive effect on their patients within 24-48 hours.  These are essentially anecdotal reports from medical professionals outside of a rigorous research setting so they should be understood as weak evidence of antidepressive effects but there is no reason they should be ignored. 

Some new studies published in the last few years are attempting to describe the possible mechanism of action of CBD with regard to depression.


CBD For Pain


CBD relieves pain in different ways than powerful opioids do.

CBD relieves pain without intoxicating you.

It won’t make your thinking foggy like an opioid painkiller.

With CBD, you can expect to keep a clear head throughout the day.

CBD feels more like it disrupts pain without the resulting “high.”

CBD doesn’t have the drawbacks you may come to expect from opioid painkillers.

CBD is non-addictive, non-habit forming, and non-intoxicating.

CBD may even be a potential treatment for opioid abuse.

CBD can diminish cravings and anxiety associated with opioid withdrawal symptoms. (21)



According to the 2018 study below, CBD effects how pain is transmitted through the nervous system to the brain. (22)



CBD may also affect the source of the pain, especially when the pain is caused by chronic inflammation.

CBD and cannabis terpenes have strong anti-inflammatory properties.

Chronic inflammation can result in many types of hard to treat pain.

By reducing inflammation, CBD may be especially suited for relieving neuropathic pain. (23)



Reducing inflammation with CBD may have other health benefits too.

Inflammation can cause cardiovascular disease and premature brain aging. (24)



And the research into pain management with cannabidiol is just getting started.

This press release from the NIH on September 19, 2019, announces a new NIH cannabinoid research initiative.



NIH will study pain management techniques using cannabinoids compounds and terpenes from cannabis.

In the next section, you’ll see how to use CBD and terpenes to affect your mood, relaxation, confidence, and more…

How CBD Works

Stick with me in this section. 

Understanding the interaction between CBD and your endocannabinoid system is important.

Knowing this biology gives you the power to control your own CBD benefits.

Do you take CBD for pain or relaxation?

Maybe you take CBD to uplift your mood?

The goal of this guide is to make sure you get the CBD benefits you want.

This section will be simple and quick.

It’ll focus on only what matters.

Let’s get started.



Endocannabinoid Receptors

Your endocannabinoid system (ECS) has two main types of cannabinoid receptors.

Dr. Ruth Ross from the video above tells you to think of cannabinoid receptors like a “lock.”

She says, think of CBD like a “key.”

When CBD comes in contact with the right receptor, it unlocks the lock.

That means, CBD binds to the receptor and sends a signal that releases to the endocannabinoid system make a change in how your body is regulating itself.

Not too technical, right?

TIP: Watch Dr. Ruth Ross’s Video for a simple explanation of how cannabinoids work


Different Cannabinoids, Different Benefits

Different types of cannabinoids bond with different receptors.

That’s why different cannabinoids cause different benefits

THC (the cannabinoid that causes a “high,” euphoric feeling) unlocks the CB1 receptor.

CBD (the non-intoxicating cannabinoid that “relaxes you“) unlocks the CB2 receptor.

That’s the difference between the two.

THC and CBD have different effects because they “unlock” different cannabinoid receptors.

That said, CBD also regulates how THC interacts with the THC receptor (CB1 receptor).

CBD down regulates how THC bonds with its CB1 cannabinoid receptor. (25)

This means that if THC gives you anxiety-like feelings, CBD can calm those feelings.

But, things don’t work the other way around.

THC does not affect the CBD receptor (CB2).

Only CBD can affect both CB1 and CB2 receptors.


Unfortunately, THC doesn’t always make people feel good. 

Sometimes THC causes anxiety instead of a euphoric feeling.

When this happens, it’s actually the THC that is making people feel anxious. (26)

Some people quit smoking marijuana completely because of these anxious feelings.

Unlike THC, CBD doesn’t cause anxious feelings. 

In fact, it has the opposite effect.

CBD relaxes people and has an anti-anxiety effect which is consistently shown in the medical literature. (27)

When CBD and THC are present at the same time, CBD calms anxious feelings caused by THC.

Medical professionals say that CBD “modulates down” how THC and the CB1 receptor interact. (28)

However technical doctors want to say it, the result is that CBD consistently provides a more relaxing experience from medical marijuana.


How are you doing?

Not too bad, right?

The next section has some AMAZING insights.



We’ve been talking about “cannabinoids” as if they come from hemp.

That’s not exactly correct.

Cannabinoids are actually something that your body makes naturally.

They’re how your endocannabinoid system sends signals within your body to regulate itself.

Cannabinoids are naturally part of how your endo-cannabinoid system regulates your body.

The cannabinoids that your body makes are called endogenous cannabinoids. (29)

The cannabinoids that come from hemp (like CBD, CBG, CBN) are really called phytocannabinoids.

“Phyto” means comes from plants.

So, CBD is actually a phytocannabinoid because it’s a cannabinoid that comes from a plant—the hemp plant.

The AMAZING thing is that phytocannabinoids like CBD are practically the exact same compound as the cannabinoids created by your body.

In fact, cannabinoids and phytocannabinoids are so similar your body can’t tell them apart. (30)

That’s the magic of hemp.

It’s practically the only plant that creates the same cannabinoid compounds that your body uses to regulate itself.

Hemp creates the chemicals our body’s use to regulate:

  • appetite
  • pain
  • memory
  • muscle recovery
  • depression
  • anxiety
  • confidence
  • fertility
  • inflammation
  • and more

That’s why CBD works.

It mimics the compounds in your body and gives you more control over your ECS.

You can use cannabinoids to boost or diminish the self-regulatory functions controlled by your ECS. (31)

Hemp essentially makes natural copies of the signaling compounds your body already uses to regulate itself.

That’s how taking hemp cannabinoids can put you in more control of your own health and mood.

Hemp is a pretty amazing plant, right?

A plant makes the same chemicals that are key to controlling how we feel and maintain our homeostasis.

It’s like some sort of magic.

However you want to look at it, hemp cannabinoids are a wellness breakthrough.

Let’s make sure you get the precise benefits you want.

Powerful Terpenes


Hemp makes additional helpful compounds other than cannabinoids.

Hemp is also full of beneficial terpenes.

If you’re interested in learning more about terpenes and how to pair them with cannabinoids to maximize the entourage effect, check out our scientific terpene guide here.

Terpenes are natural compounds that give high CBD hemp strains their delicious flavors and aroma.

The same terpenes in hemp are found in fruits and vegetables as well as essential oils used in aromatherapy. (32)

Like CBD, terpenes have health and mood benefits of their own.


Terpene Mood Benefits


According to the 2016 study below, limonene is a terpene that has an uplifting effect on mood simply as a result of its appealing odor. (33)


Limonene is naturally found in hemp and citrus.

Other terpenes have different benefits, like relaxation.

Linalool is a popular terpene that is found in lavender with anti-anxiety benefits. (34)


Additionally, linalool has a stress-relieving and relaxing effect according to multiple studies.

That’s just a few of hemp’s terpenes and their effect on mood.

There are many terpenes that affect mood and have surprising health benefits.



Terpene Health Benefits


Terpenes have a broad range of health benefits.

Terpene health benefits include:

Terpenes are useful in inflammatory skin diseases like eczema and psoriasis, treating scars, and cosmetics. (35)

Terpenes can even help protect the brain from neurodegenerative effects of aging. (36)


If you want to get more benefits from your CBD oil try adding terpenes.

Which terpenes should you add?

Check out our guide right here to the 16 important terpenes in hemp plants.

Its a simple, quick, searchable reference for everything you need to know about hemp terpenes and their benefits.



Terpene Entourage Effect


Terpenes lengthen and strengthen the benefits you get from CBD.

You can add hemp terpenes to your CBD oil or tincture to increase the benefits you get from CBD.

When terpenes and CBD are taken together, they increase the effects of both.

This is called the “entourage effect” and it has broad benefits for mood disorders and anxiety. (37)

The entourage effect is strongest when you consume full-spectrum CBD products.

In our experience dabbing CBD wax and live rosin has the ultimate entourage effect and is the most efficient method of consumption.

CBD wax contains the full spectrum of cannabinoids and the complete terpene profile found in a hemp strain.

I’m also a chef so I love infusing CBD wax into delicious recipes.

Doesn’t CBD rosin look like honey?

Potent hemp wax is full of flavorful terpenes and concentrated CBD.

CBD Health Benefits


A new initiative to study minor cannabinoids is underway now at the National Institutes of Health.

NIH researchers are publishing new CBD health benefits every month.

Let’s take a quick look at just a few of the latest CBD findings in 2020 and 2019.


CBD Sleep Benefits


Studies show cannabidiol may benefit sleep initiation and sleep duration. (38)

Taking CBD for sleep helps sleep onset insomnia and sleep maintenance insomnia.

CBD works because it gets to the root problems causing your insomnia.

Check out this scientific guide to CBD (cannabidiol) benefits for insomnia here.

CBD effects the causes of insomnia including anxiety, depression, pain, and inflammation. (39)

CBG, or cannabigerol, is another cannabinoid with benefits for insomnia. (40)

If you’re interested in more information on CBG (cannabigerol) benefits check out this comprehensive guide here.



CBD Exercise Benefits


Your ECS promotes the euphoric feeling you get from a hard workout. (41)

You know that feeling—it’s called runner’s high.


Runner’s high is a reward from your body for strenuous exercise.

It can lead to uplifting effects on mood and minimized depressed feelings.

Interesting 2016 CBD research into motivation and the mind-muscle connection is especially promising. (42)



There are many disorders for which the research above could be helpful.

Or, use CBD to supercharge your task motivation to be more productive and get more done.


CBD For Pain


CBD effects pain and changes how pain signals are relayed to the brain.  (43)

By disrupting pain signals, your ECS can relieve pain.

Cannabidiol pain-relieving properties are currently being studied for:

  • chronic pain
  • difficult to treat pain
  • palliative care
  • neuropathic pain.


CBD Fertility Benefits


Research shows cannabinoids affect embryo implantation and uterine receptivity. (44)

If cannabinoid levels in the uterus are either too low or too high then the likelihood of pregnancy is reduced.

The proper function of the endocannabinoid system is about balance.

This extends to the reproduction benefits of CBD.



CBD Immune System Benefits


The ECS affects how your immune system responds to infection. (45)

White blood cells are critical to proper immune system function.

They’re your main defenders from infection.



CBD also benefits your immune system by helping you sleep and recover.

Anxiety, stress and worry are all contributing factors to immune suppression. (46)

You are less likely to get sick if you are well rested physically and mentally.


CBD Anxiety Benefits


2017 CBD research shows cannabidiol modulates your ECS to help with anxious feelings and even panic attacks. (47)

If you struggle with anxiety check out this scientific guide to the latest medical studies.

cannabidiol guide to anxiety benefits based on latest medical studies recent to 2020


CBN is a powerful sedative and mildly psychoactive cannabinoid with even stronger anti-anxiety effects. (48)

CBN is non-habit forming and not addictive.

Research says CBN is about 10% as intoxicating as THC.



CBD Metabolism Benefits


Cannabidiol has a critical signaling role within your endocannabinoid system (ECS).

Your ECS regulates:

  • appetite
  • lipogenesis
  • anabolic processes
  • energy storage
  • energy expenditure 

Endocannabinoids are critical to controlling your metabolic rate and available energy. (49)





CBD Appetite Effects


There is a direct connection between appetite, CBD and food pleasure.

Some cannabinoids have been shown to increase hunger (THC) while others can suppress appetite and counter the tendency toward overconsumption in animal models. (50)

Cannabinoids also appear to affect the pleasure received from consuming food.




CBD Memory Effects


The ECS appears to have a significant role in long term memory creation. (51)

Additionally, CBD appears to regulate fear memory formation.

Proper regulation (extinguishing) of fear memory may play an important role in treating Post-Traumatic Stress Disorder. (52)

Traumatic memory destruction is an important function of the endocannabinoid system.

The ability to properly extinguish traumatic memories promotes wellbeing.

According to the 2019 medical study below, CBD helps PTSD by relieving anxiety from traumatic memories and potentially diminishing their recurrence. (53)

Though the mechanism is not fully understood, studies show that CBD may help to decrease the lifespan or immediate availability of traumatic memories.

Uncontrollable recurrence of traumatic memories is one of the main symptoms of PTSD.

Interested in a guide to the latest studies on CBD benefits for PTSD?  Click here.

CBD Side Effects

CBD adverse effects and toxicity are infrequent.

Side effects of cannabidiol include:

  • dry mouth
  • dizziness
  • low blood pressure
  • drowsiness

If any adverse effects do occur, you should stop taking the CBD immediately or consult about continuing use.

CBG Adverse Effects Department of Health 

Above is a highly recommended guide to cannabinoid adverse effects developed by the public health authority of the District of Columbia.  Click on the image to download it from our site.


CBD Dosage


According to a 2019 study, CBD is tolerated across a wide dosing range.

CBD research shows that taking up to 1500mg/day orally showed no psychomotor slowing, vital sign abnormalities or negative mood effects. (54)



Video: CBD Dosage

Check out this quick video on CBD dosage for beginners.


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  2. Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). “Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders”Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389PMC 3481531PMID 23108553.
  3. Pisanti S, Malfitano AM, Ciaglia E, Lamberti A, Ranieri R, Cuomo G, Abate M, Faggiana G, Proto MC, Fiore D, Laezza C, Bifulco M (July 2017). “Cannabidiol: State of the art and new challenges for therapeutic applications”. Pharmacol. Ther175: 133–150. doi:10.1016/j.pharmthera.2017.02.041PMID 28232276.
  4. Fischer B, Russell C, Sabioni P, van den Brink W, Le Foll B, Hall W, Rehm J, Room R (August 2017). “Lower-Risk Cannabis Use Guidelines: A Comprehensive Update of Evidence and Recommendations”American Journal of Public Health107 (8): e1–e12. doi:10.2105/AJPH.2017.303818PMC 5508136PMID 28644037.
  5. Mead, Alice (2017). “The legal status of cannabis (marijuana) and cannabidiol (CBD) under U.S. law”Epilepsy and Behavior (Review)70 (Pt B): 288–291. doi:10.1016/j.yebeh.2016.11.021ISSN 1525-5050PMID 28169144.
  6. Zou S, Kumar U. Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System. Int J Mol Sci. 2018;19(3):833. Published 2018 Mar 13. doi:10.3390/ijms19030833
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