Published November 1, 2019
- In a double-blind placebo-controlled study at NYU, cannabidiol “significantly reduced both craving and anxiety” caused when heroin addicts were exposed to drug cues.
- CBD reduced heart rate response prompted by drug cues
- CBD reduced salivary cortisol levels prompted by drug cues.
- CBD caused “no significant effects on cognition”
- CBD caused “no serious adverse effects” (1)
Summary This double-blind randomized placebo-controlled study assessed heroin addicts who were given CBD to help them reduce cravings and anxiety while attempting to quit heroin. (2)
- Addicts were given either a 400mg CBD dose or an 800mg CBD dose daily for 3 days.
- Addicts were assessed 1 hour, 2 hours and 24 hours after taking the CBD product.
- They were also assessed again 7 days after finishing the 3-day course of 400mg or 800mg dose of CBD. (3)
Addicts were assessed for:
- drug craving
- positive and negative affect
- physiological status (4)
- In the CBD group (and not in the placebo group) addicts cravings for heroin and anxiety were significantly reduced.
- there is a “strong basis for further investigation of [cannabidiol] as a treatment option for opioid use disorder.” (5)
CBD significantly reduces chronic pain, neuropathic pain, and hard to treat pain according to multiple medical studies. Check out this guide to CBD benefits for pain relief.
Video: CBD benefits for Opioid Abuse
Keywords: CBD; Heroin Addiction; Substance Abuse; Cannabis; Opioid Use Disorder
Hurd YL, Spriggs S, Alishayev J, et al. Cannabidiol for the Reduction of Cue-Induced Craving and Anxiety in Drug-Abstinent Individuals With Heroin Use Disorder: A Double-Blind Randomized Placebo-Controlled Trial. Am J Psychiatry. 2019;176(11):911–922. doi:10.1176/appi.ajp.2019.18101191