2020 Study: CBD Helps IBD, Improves Quality Of Life

 

2020 Study: CBD significantly improves quality of life for those with Colitis and Crohn's Disease. #cbd tell a friend

 

 

cannabidiol inflammatory bowel disease treatment

 Published January 4, 2020

 

 

 

 

 

Study Results

  • Individuals with inflammatory bowel disease have quality of life improvements after taking CBD.  (1)                                                                 cannabigerol health benefits                    
  • CBD and CBG demonstrate beneficial effects in preclinical models of intestinal inflammation. (2)                                                                                CBG health benefits

 

 

 

Background 

  • Cannabinoids made by the human body “have shown a regulatory role in inflammation and mucosal permeability of the gastrointestinal tract.”
  • It is believed that endocannabinoids (those made by the human body) likely interact with the gut microbiome to regulate inflammation and mucosal permeability. (3)

 

cannabinoids gut health

 

CBD User Reports

 

Cannabis is reported by users to:

  • block the sensation of pain in the gut
  • have anti-inflammatory properties
  • antidiarrheal properties (4)

CBD health benefits

 

Conclusion

While strong evidence of CBD’s beneficial effects on gastrointestinal diseases is still lacking, clinical trials of individuals with inflammatory bowel disease have shown improvement in quality of life even if they haven’t shown evidence of a reduction in inflammation. (5)

 

CBD crohns treatment

 

 

Download The CBD Research

 

 

 

Video: CBD benefits for Inflammatory Bowel Disease

Study Authors

 

Kienzl M

Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz

 

Storr M

Zentrum für Endoskopie

Department of Medicine, Ludwig-Maximilians University

 

Schicho R

Division of Pharmacology, Otto Loewi Research Center, Medical University of Graz

BioTechMed Graz

 

Keywords: Cannabis sativa; abdominal pain; diarrhea; inflammatory bowel diseasecannabidiol; endocannabinoid system;

References

Kienzl M, Storr M, Schicho R. Cannabinoids and Opioids in the Treatment of Inflammatory Bowel Diseases. Clin Transl Gastroenterol. 2020;11(1):e00120. doi:10.14309/ctg.0000000000000120

2019 Study: CBD For Crohn’s Disease

 

2019 Study: CBD improved Crohn's patient's symptoms from 14 to 7 on the Harvey-Bradshaw Index. #cbd #crohns #ibd tell a friend

 

Study Results

 

After taking CBD, patients had a substantial improvement in their Chrohn’s Disease symptoms.  Patients’ average score on the Harvey-Bradshaw Index (a way of measuring Crohn’s disease symptoms) improved from  14 to 7. (1)

 

cbd ibd clinical trial benefits

 

CBD Dosage

  • The average dose of CBD consumed by patients to treat inflammatory bowel disease was 31 grams of cannabis per month.
  • This CBD research found that most patients responded well to an inflammatory bowel disease treatment of 21mg/day THC and 170 mg/day CBD.
  • The researchers conclude that “the majority of inflammatory bowel disease patients using cannabis are satisfied with a dose of 30 g/month.” (2)

 

 

 

 

 

 

cbd ibd benefits
Published November 13, 2019

Summary

 

This CBD research assessed the effects of using medical cannabis for treating inflammatory bowel disease. (3)

CBD dose and method of consumption, “adverse events, use of other medications, and long-term effects were evaluated among 127 patients with inflammatory bowel disease using legalized medical cannabis.” (4)

Evaluation

 

Patients were tested for:

  • Blood count
  • albumin
  • C-reactive protein

Patients were tested within one month of starting cannabidiol treatment for inflammatory bowel disease and at least one year after the therapy was started. (5)

Patients and one significant family member also completed questionnaires on:

  • disease activity
  • patient function
  • signs of addiction (6)

cannabidiol ibd medical study nih

 

Additional outcomes

  • There was a small but statistically significant gain in weight of about 4 lbs. per patient.
  • The use of other medications for inflammatory bowel disease decreased significantly after cannabis treatment was started.
  • The employment of the patients increased from 65% to 74%. (7)

 

Adverse effects

 

Researchers state they did not observe “negative effects of cannabis use on the patients’ social or occupational status.” (8)

 

 

Download The CBD Research

 

Video: CBD benefits for Inflammatory Bowel Disaese.

Study Authors

 

Naftali T

Meir Medical Center Institute of Gastroenterology and Hepatology, Kfar Saba

Sackler School of Medicine, Tel Aviv University, Tel Aviv

 

Bar-Lev Schleider L

Soroka University Medical Centre and Faculty of Health Sciences, Ben-Gurion University of the Negev

 

Sklerovsky Benjaminov F

Meir Medical Center Institute of Gastroenterology and Hepatology, Kfar Saba

Sackler School of Medicine, Tel Aviv University, Tel Aviv

 

Lish I

Meir Medical Center Institute of Gastroenterology and Hepatology, Kfar Saba

Sackler School of Medicine, Tel Aviv University, Tel Aviv

 

Konikoff FM

Meir Medical Center Institute of Gastroenterology and Hepatology, Kfar Saba

Sackler School of Medicine, Tel Aviv University, Tel Aviv

 

Ringel Y

Meir Medical Center Institute of Gastroenterology and Hepatology, Kfar Saba

Sackler School of Medicine, Tel Aviv University, Tel Aviv

 

Keywords: Cannabis sativa; inflammatory bowel disease; colon; abdominal pain; cannabidiol; endocannabinoid system; crohn’s disease

References

Naftali T, Bar-Lev Schleider L, Sklerovsky Benjaminov F, Lish I, Konikoff FM, Ringel Y. Medical cannabis for inflammatory bowel disease: real-life experience of mode of consumption and assessment of side-effects. Eur J Gastroenterol Hepatol. 2019;31(11):1376–1381. doi:10.1097/MEG.0000000000001565

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