2020 CBD Research

Does Medical Cannabis help insomnia caused by chronic pain?

 

New Research Says: Yes

cbd research results

 

Study Results: After factoring in variations for “age, sex, pain level, and use of [other] sleep and anti-depressant medications,” patients showed improvement in their sleep.

Who Benefits: Patients over the age of 50 with insomnia caused by chronic pain.

Benefit:

  • Medical cannabis appeared to help patients stay asleep and kept them from waking up during the night.
  • Medical cannabis did not affect how quickly patients fell asleep nor the overall duration of their sleep.

cannabidiol insomnia treatment

Possible adverse effects:  Frequent use of cannabis may not improve sleep.

Frequent medical cannabis users reported:

  • increased difficulty falling asleep
  • increased difficulty staying asleep the whole night

cannabidiol study results graph

 

cannabidiol sleep analgesic

Pain Research Published On January 20, 2020

Our Summary:  More patients are preferring to take medical cannabis for their chronic pain and insomnia symptoms.

cannabidiol pain treatment

In this study: 128 patients over the age of 50 were recruited from a local pain clinic.

66 were medical cannabis users and 62 did not use medical cannabis.

cannabidiol pain study

Analysis: Predictive modeling was used to assess the sleep differences in the two groups.

cbd pain insomnia

Statistical correlations were also made between sleep and the properties of the medical cannabis used such as:

  • dose
  • length of use
  • frequency of use
  • number of strains used
  • tetrahydrocannabinol levels
  • cannabidiol levels

pain cbd treatment

Conclusion: The results of the study associated medical cannabis use with fewer Sleep Maintenance Insomnia symptoms but medical cannabis use did not affect Sleep Onset Insomnia nor overall sleep duration in older patients with chronic pain.

 

 

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Check out this quick video to learn how people are using medical cannabis for chronic pain relief.

 

Study Authors:

Sznitman SR

School of Public Health, University of Haifa Faculty of Social Welfare and Health Sciences

 

Vulfsons S 

Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology

Institute of Pain Medicine, Rambam Health Care Campus

Meiri D

Department of Biology, Technion Israel Institute of Technology

Weinstein G

School of Public Health, University of Haifa Faculty of Social Welfare and Health Sciences

Keywords: chronic pain; insomnia; medical cannabis; sleep

2019 CBD Research

CBD for neuropathic pain relief?

New Study Results Say: Yes

cbd study research results

 

Study Results:   There was a “significant reduction in intense pain, sharp pain, cold and itchy sensations in the CBD group when compared to the placebo group.”

cbd pain benefit

Who Benefits:

  • Patients with chronic pain and neuropathic pain not caused by cancer.
  • The average age of patients in the study was 68 years

Benefit:

  • The researchers concluded that transdermal application (topical CBD cream) can relieve pain in patients with peripheral neuropathy.  
  • CBD cream may provide an alternative to other treatments for neuropathic pain.

Adverse Effects: There were no adverse events noted in this study.  Cannabidiol was well tolerated by all participants with minimal to no side effects in this study.

 

cannabidiol research 2019

cbd treatment neuropathic pain 2019 research

New CBD Research Published December 1, 2019

Our summary:  This new CBD research aims to examine the pain-relieving properties of topical CBD cream for the treatment of chronic and neuropathic pain not caused by cancer.

By the numbers:

  • 4 week
  • randomized
  • placebo-controlled
  • 29 patients with neuropathic pain symptoms  (divided in two groups)

cbd pain study

Topical CBD Cream Dosage: One group received a CBD topical cream dose of 250 mg CBD/3 fl. oz while the other received a placebo.  

After 4 weeks the placebo group was allowed to transfer over to receive treatment with the CBD cream.

Patients:

  • The participants in the study had an average age of 68 years. 
  • Two-thirds were male and one-third female.

 

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Check out this quick video about CBD for neuropathic pain relief.

Study Authors:

Xu DH

PGY-2, Department of Podiatric Medicine and Surgery, Scripps Mercy Hospital, San Diego, CA 92103, United States

Cullen BD

Podiatric Surgery Section Chief, Scripps Mercy Hospital, San Diego, 92103, United States.

Tang M

Department of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, United States

Fang Y

Department of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, United States

Keywords: CBD; Chronic Pain; Cannabis sativa; Diabetic neuropathy; Hemp; Nerve pain; Review

2019 CBD Research

Can CBD help chronic pain patients stop taking opioid painkillers?

 

New Study Results Say: Yes—53% reduced or eliminated opioid painkillers.

cbd study research results

 

Study Results:  

  • 53% of chronic pain patients reduced or eliminated their prescribed opioid use within 8 weeks of adding CBD to their pain treatment.
  • 94% of study participants reported quality of life improvements from taking CBD.
  •  strong relationship between CBD and improvements in chronic pain intensity as well as better sleep quality.

cbd chronic pain

Who benefits:

  • Ages 30-65
  • taking opiates prescribed by a doctor for more than 1 year
  • patients with chronic pain

Benefit: 

  • reduce or eliminate opiates from pain management treatment
  • better sleep
  • improved reported quality of life

cbd pain relief

Conclusion: Cannabidiol could reduce opioid use and improve the quality of sleep for patients who take pharmaceutical opiates for chronic pain.

cannabidiol study results graph
cbd pain research

 

New CBD Research Published November 12, 2019

Our summary:  131 patients were recruited from a pain management clinic.

Of the 131 patients, 97 completed the 8 week CBD research study.

Patients were ages 30-65.

Before the study, patients were using opioids for at least one year to treat chronic pain symptoms.

cannabidiol pain relief

Evaluation: Improvements in chronic pain symptoms were evaluated using 4 tests:

  • Pain Disability Index (PDI-4) (positive trend results, but not significant)
  • Pittsburgh Sleep Quality Index (PSQI) (a significant improvement from CBD use)
  • Pain Intensity and Interference (PEG) (a significant improvement from CBD use)
  • Patient Health Questionnaire (PHQ-4) (positive trend results, but not significant)

cannabidiol pain research

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 Check out this helpful video to see the definition of Opioid Use Disorder and its symptoms.

 

 

Study Authors:

Capano A

Ecofibre Ltd, Philadelphia, PA, USA

Lambert Center for the Study of Medicinal Cannabis & Hemp Philadelphia

 Weaver R

University of Louisville

 

Burkman E

University of Louisville

Keywords: Cannabinoid; cannabidiol; cannabis; chronic pain; opioids; sleep

2018 CBD Research

cannabidiol pain insomnia

CBD Study Published August 2018

Our Summary:  This CBD study focuses on the delivery method of cannabinoids such as cannabidiol for pain and inflammation.

cannabidiol bowel pain

Benefits: CBD has possible benefits for treating a wide variety of conditions including:

  • pain
  • inflammation
  • epilepsy
  • sleep disorders
  • symptoms of multiple sclerosis
  • anorexia
  • schizophrenia
  • and more

Types of CBD: This study is a review of different methods for delivering CBD for treating pain and inflammation including oral, transdermal and nanotechnology-based drug delivery strategies.

cbd pain treatments

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Study Authors:

Natascia Bruni

natascia.bruni@candioli.it

Istituto Farmaceutico Candioli, 10092 Beinasco, Italy

Carlo Della Pepa

carlo.dellapepa@unito.it

Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy

Simona Oliaro-Bosso

simona.oliaro@unito.it

Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy

Enrica Pessione

enrica.pessione@unito.it

Department of Life Sciences and Systems Biology, University of Turin, 10123 Turin, Italy

Daniela Gastaldi

daniela.gastaldi@unito.it

Department of Molecular Biotechnology and Health Sciences, University of Turin, 10125 Turin, Italy 

Dosio F

franco.dosio@unito.it

Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy

 

Keywords: cannabidiol; cannabinoids; delivery system; inflammation; pain treatment; Δ9-tetrahydrocannabinol

2018 CBD Research

nih research cbd pain

 

CBD Study Published November 2018

History:

  • Cannabinoids have been used for treating medical conditions for thousands of years.
  • Cannabis as medicine stopped during the mid-twentieth century due to the prohibition against marijuana.

Our Summary:  

Cannabis and CBD hold substantial promise for treating:

  • pain
  • chronic pain
  • neuropathic pain

Adverse Effects: Cannabidiol side effects are minimal to moderate according to the study and generally stop if treatment is ended.

cbd analgesic benefits

Conclusion:

  • There is a lack of information as to the long term effects of using cannabis and cannabinoids for treating pain.
  • More research needs to be conducted to confirm its cannabidiol’s long term safety record.

 

 

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Study Authors:

Sonja Vučković

Department of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Dragana Srebro

Department of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Katarina Savić Vujović

Department of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Čedomir Vučetić

Clinic of Orthopaedic Surgery and Traumatology, Clinical Center of Serbia, Belgrade, Serbia

Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Milica Prostran

Department of Pharmacology, Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia

Keywords: animals; cannabis/cannabinoids; efficacy; humans; pain; pharmacodynamics; pharmacokinetics; safety

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