cannabidiol treatment alcohol abuse disorder

CBD Reduces Alcohol Cravings And Withdrawal

These study summaries provide fact-based answers about CBD benefits for alcoholism and withdrawal.

  • how to use CBD for alcoholism
  • see exactly how CBD benefits alcohol withdrawal and cravings
  • discover the optimal CBD dosage tested and possible adverse effects
  • find out how this nonintoxicating compound affects Alcohol Use Disorder

If you don’t find an answer in this guide to a question you have, leave us a comment below. We’ll search the published studies to see if an answer exists and get back to you.

Let’s get started.

 

CBD May Treat Alcohol Use Disorder

  • This is a scientific study
  • CBD may protect the brain from the adverse effects of alcohol

2019 Study: CBD reduces alcohol cravings and withdrawal for alcoholics, 2019 study. #cbd tell a friend

  

Published April 14, 2019

Study Results

 According to a survey of CBD for Alcoholism studies, cannabidiol is a promising treatment for Alcohol Use Disorder. (1)

cannabidiol alcoholism withdrawal

 

Benefit

  • CBD protected the brain from some adverse effects of alcohol use in preclinical and lab trials.  (2)

cbd alcoholism benefit

 

  • CBD decreased liver toxicity and alcohol-induced fatty liver in animals.  (3)

cannabidiol alcoholism effect

 

CBD decreased symptoms of alcohol abuse
  • cue-elicited and stress-elicited alcohol-seeking
  • alcohol self-administration
  • withdrawal-induced convulsions
  • impulsive discounting of delayed rewards (4)

 

Adverse Effects

CBD was well tolerated with minimal side effects in human trials. (5)

cannabidiol alcoholism treatment

CBD is non-addictive.

 

Summary

This study was a review of medical literature and research for the therapeutic potential of CBD in cases of Alcoholism.

The researchers analyzed 12 articles on CBD for alcoholism:

  • 8 using rodent models
  • 3 using healthy adult volunteers
  • 1 using cell culture

 

Neuroprotectorant

In both rodent and cell cultures, evidence was found for CBD having neuroprotective effects on the hippocampus area of the brain. (6)

 

Liver

In rodent models, cannabidiol was found to have protective effects on the liver, specifically fatty liver disease associated with alcoholism.  (7)

 

Alcohol Cravings

In rodent models, CBD was also found to have a number of effects that could be helpful for addicts who are trying to quit using alcohol.  It appears that CBD may decrease alcohol cravings and specific alcohol withdrawal symptoms in rodents.  (8)

What’s Next

With regard to human clinical research, this study states there is a lack of human trials to show that these preclinical findings are effective in people who struggle with Alcohol Use Disorder.

 

Conclusion

 “Human preclinical and clinical studies are needed to determine whether these positive effects in model systems substantively translate into clinically relevant outcomes.” (9)

 

Download The CBD Research

Interested in the benefits of CBD for PTSD? Check out this guide to CBD benefits for PTSD.

 

 

 

Video: CBD for alcohol withdrawal

 

Study Authors

Turna J

Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Peter Boris Centre for Addictions Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Syan SK

Peter Boris Centre for Addictions Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Department of Psychology, Neuroscience, and Behavior, McMaster University, Hamilton, Ontario, Canada

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

Frey BN

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

Mood Disorders Program and Women’s Health Concerns Clinic, St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Rush B

Centre for Addiction and Mental Health, Toronto, Ontario, Canada

Homewood Research Institute, Guelph, Ontario, Canada

Costello MJ

Homewood Research Institute, Guelph, Ontario, Canada

Weiss M

Addiction Medicine Service, Homewood Health Centre, Guelph, Ontario, Canada

MacKillop J

Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Peter Boris Centre for Addictions Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Department of Psychology, Neuroscience, and Behavior, McMaster University, Hamilton, Ontario, Canada

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

Homewood Research Institute, Guelph, Ontario, Canada

Keywords: Cannabis, Cannabidiol, Alcoholism, alcohol use disorder, alcohol abuse

 

References

Turna J, Syan SK, Frey BN, et al. Cannabidiol as a Novel Candidate Alcohol Use Disorder Pharmacotherapy: A Systematic Review. Alcohol Clin Exp Res. 2019;43(4):550–563. doi:10.1111/acer.13964

CBD Decreases Alcohol Abuse In Surprising Ways

 

CBD reduces alcohol cravings by repairing microbiota-gut-brain-axis, 2019 study. #cbd tell a friend

 

cannabidiol alcoholism benefits

Published December 2019

 

Study Results

CBD shows promise diminishing symptoms of alcohol use disorder. (1)

 

cannabidiol alcoholism study

Summary

  • This study discusses how the endocannabinoid system may have important implications for cannabidiol treatments for alcoholism.
  • The aim is to guide the thinking of future researchers and create a framework to study the relationship between cannabidiol and alcohol use disorder.
  • Develop a theoretical framework for the effects of cannabinoids such as CBD on alcoholism. (2)

How CBD Works

While it is not currently known exactly how CBD helps diminish symptoms of alcoholism, there are a number of proposed mechanisms:

  • CBD may affect brain functions which lead to alcohol consumption and abuse (3)

cannabidiol alcoholism study

 

  • CBD may influence alcohol abuse by effecting “digestive, immune, and central nervous systems, collectively known as the microbiota-gut-brain-axis (MGBA).” It appears CBD can repair disturbances in these systems which may have the result of reducing cravings for alcohol.  (4)                                                                                                                                                                                                                 

cannabidiol alcoholism study

 

Video: CBD benefits for quitting alcohol.

 

Download The CBD Research

 
 

Study Authors

 

Hollis C. Karoly

Institute of Cognitive Science, University of Colorado Boulder

 

Keywords: Cannabis, Cannabidiol, Alcoholism, alcohol use disorder, alcohol abuse, 

 
 

References

Karoly HC, Mueller RL, Bidwell LC, Hutchison KE. Cannabinoids and the Microbiota-Gut-Brain Axis: Emerging Effects of Cannabidiol and Potential Applications to Alcohol Use Disorders. Alcohol Clin Exp Res. 2020;44(2):340–353. doi:10.1111/acer.14256

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