CBD Reduces Cravings

This is a scientific guide.

Based on the latest medical studies.

  • know exactly how CBD affects withdrawal and cravings
  • discover the optimal CBD dosages tested and possible adverse effects
  • find out how this nonintoxicating compound affects Alcohol Use Disorder

Let’s get started.

 

2019 CBD Research

CBD for Alcoholism?

New Study Results Say: Promising 

New CBD Research Published April 14, 2019

cbd research results

Study results:  According to a survey of CBD for Alcoholism studies, cannabidiol is a promising treatment for Alcohol Use Disorder. (1)

cannabidiol alcoholism withdrawal

Benefit:

  • CBD protected the brain from some adverse effects of alcohol use in preclinical and lab trials.  (2)                                                cbd alcoholism benefit
  • CBD decreased liver toxicity and alcohol-induced fatty liver in animals.  (3)                                                                                           cannabidiol alcoholism effect

CBD decreased symptoms of alcohol abuse:

  • cue-elicited and stress-elicited alcohol-seeking
  • alcohol self-administration
  • withdrawal-induced convulsions
  • impulsive discounting of delayed rewards (4)

Adverse Effects: CBD was well tolerated with minimal side effects in human trials. (5)

cannabidiol alcoholism treatment

CBD is non-addictive.

cannabidiol study results graph

Our Summary:  This study was a review of medical literature and research for the therapeutic potential of CBD in cases of Alcoholism.

The researchers analyzed 12 articles on CBD for alcoholism:

  • 8 using rodent models
  • 3 using healthy adult volunteers
  • 1 using cell culture

Neuroprotectorant: In both rodent and cell cultures, evidence was found for CBD having neuroprotective effects on the hippocampus area of the brain. (6)

Liver: In rodent models, cannabidiol was found to have protective effects on the liver, specifically fatty liver disease associated with alcoholism.  (7)

Alcohol Cravings: In rodent models, CBD was also found to have a number of effects that could be helpful for addicts who are trying to quit using alcohol.  It appears that CBD may decrease alcohol cravings and specific alcohol withdrawal symptoms in rodents.  (8)

What’s Next: With regard to human clinical research, this study states there is a lack of human trials to show that these preclinical findings are effective in people who struggle with Alcohol Use Disorder.

Conclusion:  “Human preclinical and clinical studies are needed to determine whether these positive effects in model systems substantively translate into clinically relevant outcomes.” (9)

 

 

Download The CBD Research

Check out this  video using CBD for alcohol withdrawal.

Study Authors:

Turna J

Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Peter Boris Centre for Addictions Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Syan SK

Peter Boris Centre for Addictions Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Department of Psychology, Neuroscience, and Behavior, McMaster University, Hamilton, Ontario, Canada

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

Frey BN

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

Mood Disorders Program and Women’s Health Concerns Clinic, St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Rush B

Centre for Addiction and Mental Health, Toronto, Ontario, Canada

Homewood Research Institute, Guelph, Ontario, Canada

Costello MJ

Homewood Research Institute, Guelph, Ontario, Canada

Weiss M

Addiction Medicine Service, Homewood Health Centre, Guelph, Ontario, Canada

MacKillop J

Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Peter Boris Centre for Addictions Research, McMaster University & St. Joseph’s Healthcare Hamilton, Hamilton, Ontario, Canada

Department of Psychology, Neuroscience, and Behavior, McMaster University, Hamilton, Ontario, Canada

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

Homewood Research Institute, Guelph, Ontario, Canada

 

Keywords: Cannabis, Cannabidiol, Alcoholism, alcohol use disorder, alcohol abuse, 

References

Turna J, Syan SK, Frey BN, et al. Cannabidiol as a Novel Candidate Alcohol Use Disorder Pharmacotherapy: A Systematic Review. Alcohol Clin Exp Res. 2019;43(4):550–563. doi:10.1111/acer.13964

2019 CBD Research

cannabidiol alcoholism benefits

New CBD Research Published December 2019

Benefit:  CBD shows promise diminishing symptoms of alcohol use disorder. (1)

cannabidiol alcoholism study

Our Summary:

  • This study discusses how the endocannabinoid system may have important implications for cannabidiol treatments for alcoholism.
  • The aim is to guide the thinking of future researchers and create a framework to study the relationship between cannabidiol and alcohol use disorder.
  • Develop a theoretical framework for the effects of cannabinoids such as CBD on alcoholism. (2)

How CBD works: While it is not currently known exactly how CBD helps diminish symptoms of alcoholism, there are a number of proposed mechanisms:

  • CBD may affect brain functions which lead to alcohol consumption and abuse (3)                                                                                                         cannabidiol alcoholism study                
  • CBD may influence alcohol abuse by effecting “digestive, immune, and central nervous systems, collectively known as the microbiota-gut-brain-axis (MGBA).” It appears CBD can repair disturbances in these systems which may have the result of reducing cravings for alcohol.  (4)                                                                                                                                                                                                                 cannabidiol alcoholism study

 

 Check out this video on CBD benefits for quitting alcohol and managing anxiety.

 

Download The CBD Research

 

Study Authors:

 

Hollis C. Karoly

Institute of Cognitive Science, University of Colorado Boulder

 

Keywords: Cannabis, Cannabidiol, Alcoholism, alcohol use disorder, alcohol abuse, 

References

Karoly HC, Mueller RL, Bidwell LC, Hutchison KE. Cannabinoids and the Microbiota-Gut-Brain Axis: Emerging Effects of Cannabidiol and Potential Applications to Alcohol Use Disorders. Alcohol Clin Exp Res. 2020;44(2):340–353. doi:10.1111/acer.14256

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