Extinguish Fear Memory

This is a scientific guide.

Based on the latest medical studies.

  • know exactly how CBD affects PTSD causes and symptoms
  • discover the optimal CBD dosage tested and adverse effects

Let’s get started.

2019 CBD Research

CBD affects fear memory recall

 

cbd post-traumatic stress disorder benefit

New Research Published August 1, 2019

cbd research results

Study Results:

  • CBD did significantly reduce fear memory recall in animal models.
  • THC did not have the same effect as CBD when THC was taken alone.
  • When THC and CBD were taken together, there was a significant reduction in fear memory.
  • There was evidence that terpenes or other lesser cannabinoids had effects similar to CBD.
  • A mix of terpenes, flavonoids and lesser cannabinoids significantly reduced fear memories when taken in isolation and when taken with THC. (1)

 

cannabidiol study results graph

 

 

Our summary:  According to this new peer-reviewed CBD research for Post-Traumatic Stress Disorder, CBD and THC may help diminish fear learning and fearful memory creation in mammals. (2)

CBD ptsd treatment

Background:

  • The CB1 receptor is part of the endocannabinoid system and located throughout the brain.
  • CBD and THC are known to affect the CB1 receptor.
  • People with PTSD are known to have increased CB1 receptor density in the brain.
  • Patients with PTSD also have less of a natural chemical compound called anandamide.
  • Anandamide is a compound created by your endocannabinoid system.
  • Anandamide interacts with the CB1 receptor.
  • CBD mimics the anandamide made by your body and interacts with the CB1 receptor. (3)

CBD PTSD therapy

So, individuals with PTSD are known to have a high density of the type of receptors (CB1) which respond to cannabidiol and a lack of the natural chemical in the body that CBD mimics.

This suggests that taking CBD may be a promising treatment for PTSD. (4)

ptsd symptom benefit

Conclusion: This CBD study aimed to find out if CBD and THC could block or diminish memories of fearful situations in lab animals as a stepping stone to developing a CBD treatment for PTSD. (5)

fear memory symptom

 

 

 

 

Download The CBD Research

 

Check out this quick video on CBD for PTSD.

Study Authors:

Murkar A

The Royal’s Institute of Mental Health Research affiliated with the University of Ottawa

 

Kent P

The Royal’s Institute of Mental Health Research affiliated with the University of Ottawa

 

Cayer C

The Royal’s Institute of Mental Health Research affiliated with the University of Ottawa

Centre for Advanced Research in Environmental Genomics, Ottawa-Carleton Institute of Biology

James J

The Royal’s Institute of Mental Health Research affiliated with the University of Ottawa

 

Durst T

Department of Chemistry and Biomolecular Sciences, University of Ottawa

 

Merali Z

The Royal’s Institute of Mental Health Research affiliated with the University of Ottawa

Department of Neuroscience, Faculty of Science, Carleton University

Department of Cellular and Molecular Medicine, School of Psychology, University of Ottawa

 

Keywords: CBD; THC; blockade; cannabinoids; cannabis; fear; memory; reconsolidation

References

Murkar A, Kent P, Cayer C, James J, Durst T, Merali Z. Cannabidiol and the Remainder of the Plant Extract Modulate the Effects of Δ9-Tetrahydrocannabinol on Fear Memory Reconsolidation. Front Behav Neurosci. 2019;13:174. Published 2019 Aug 1. doi:10.3389/fnbeh.2019.00174

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