Changing CBD/THC Ratio

This is a scientific guide.

Based on the latest medical studies.

  • know exactly how cannabinoid ratios have changed in black-market cannabis
  • know the adverse effects of rising THC levels and decreasing CBD concentrations
  • find out how the chemistry of black market cannabis has changed over 17 years

Let’s get started.

2019 CBD Research

Does recreational marijuana make you feel anxious?

 

If so, here’s why…

cbd research results

Study Results:  From 2000-2017 the THC:CBD ratio in recreational marijuana seized from the black market increased 314%.  The THC to CBD ratio rose from 1.4/1 THC:CBD to a peak of 4.4/1 THC:CBD. (1)

cannabinoid content effects

thc cbd ratio

Importance: CBD regulates how THC makes you feel.

  • CBD is known to “down-regulate” THC absorption and decreases feelings of anxiety.  (2)                                                                                            cannabidiol thc ratio
  • THC is known to cause anxiety and mental health problems in some individuals.   (3)                                                                                                                                                                         thc mental health

 

THC increase: THC content grew dramatically from an average of 8.3% in 2000 to an average of 25.3% by 2017 while CBD content remained constant at about 6%. (4)

 


cannabidiol bowel study

 

New CBD Study Published August 21 2019

 

Our summary:  Illicit marijuana seized from the black market in Denmark from 2000-2017 was tested for THC and CBD content.

CBD THC ratio

Goal:

  • The aim of this study was to see how the overall content of THC and CBD changed over time.
  • The research also studied how the ratio of THC to CBD changed in recreational marijuana. (5)

Facts: THC causes anxiety in some people while CBD is believed to relieve anxiety.

  • CBD also regulates (or “down modulates”) how THC interacts with the CB1 receptor in your endocannabinoid system.
  • An increasing ratio of THC vs CBD may account for a rise in anxiety symptoms among recreational marijuana smokers while intoxicated. (6)

medical cannabis cbd

Results:

  • THC rose from a mean average in 2000 of 8.3% to a mean average THC content in 2017 of 25.3%.
  • CBD average content remained stable during this time period.
  • After 2011, low THC recreational marijuana was no longer available in the black market. (7)

thc cbd ratio

Conclusion: This dramatic rise in THC—and the ratio of THC to CBD—may pose a risk to public health. (8)

 

We disagree: As to THC posing a public health risk, we respectfully disagree but marijuana smokers should be aware of the changing nature of their “high” and some of the biological reasons for the change.

One of the benefits of legalization is better knowledge and sharing of scientific information about marijuana and hemp.

 

 

Download The CBD Research

 

 

Check out this quick video by Dr. Ruth Ross about cannabinoids and the endocannabinoid system.

 

 

Study Authors:

 

 

Rømer Thomsen K

Centre for Alcohol and Drug Research

 

Lindholst C

Department of Forensic Medicine

 

Thylstrup B

Centre for Alcohol and Drug Research

 

Kvamme S

Centre for Alcohol and Drug Research

 

Reitzel LA

Department of Forensic Medicine

 

Worm-Leonhard M

Department of Forensic Medicine

 

Englund A

Department of Psychosis Studies.

 

Freeman TP

Addiction and Mental Health Group (AIM)

 

Hesse M

Centre for Alcohol and Drug Research

 

Keywords: Cannabis sativa; cannabidiol; endocannabinoid system; THC;

References

Rømer Thomsen K, Lindholst C, Thylstrup B, et al. Changes in the composition of cannabis from 2000-2017 in Denmark: Analysis of confiscated samples of cannabis resin. Exp Clin Psychopharmacol. 2019;27(4):402–411. doi:10.1037/pha0000303

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