cbg guide to anxiety pain inflammation benefits

CBG: What’s all the buzz?

This guide to the benefit of CBG for anxiety and pain relief will give you fact-based answers to your questions.

  • learn how to use CBG
  • learn its exact benefits
  • learn how CBG affects mood, health, and emotions
  • learn techniques to optimize CBG benefits
  • learn how to recognize possible adverse effects

If you don’t find an answer in this guide to a question you have, leave us a comment below and we’ll search the published studies to see if an answer exists and get back to you.

Let’s get started.

What is CBG?

CBG is a cannabinoid compound made by cannabis plants.  Cannabigerol (CBG) is not intoxicating like THC. It won’t make you feel ” high” and will not cause you to fail a drug test.

But, CBG does have significant mind and mood-altering effects and is known for its potent relaxing effects.

CBG Health Benefits

CBG has critical health benefits for:

  • pain
  • inflammation
  • anxiety
  • specific types of cancer (3)
  • inflammatory bowel disease (4)
  • neuroprotective qualities (5)

While the medical community can see the positive results from CBG,  this new cannabinoid’s exact method of action is still being studied.

 

cannabigerol price demand study

 

 

CBG Mood-Altering Effects

CBG helps with specific types of anxiety and anxiety disorders. (1)


cbg anxiolytic benefits

Interested in the extensive effects of cannabinoids on anxiety disorders? Check out this guide to CBD’s scientifically backed anxiety benefits.

 

CBG Pain Benefits

According to the medical study below, CBG is unusually capable of relieving difficult to treat pain and may be an effective muscle relaxer. (2)

cbg analgesic benefits

 

 

CBG Legal Status

Since the 2018 Farm Bill passed congress, CBG and CBD derived from hemp plants are federally legal. (9)

So…what is hemp?

Hemp and marijuana are taxonomically (genus and species) the same plant. But, there’s actually a big difference between the two when it comes to federal law.

Hemp and marijuana are both cannabis plants but hemp plants are bred to produce cannabinoids like CBD and CBG.  Hemp plants have had the ability to produce THC bred out of them.

Hemp plants produce “virtually” no THC.

THC is the cannabinoid that causes a euphoric feeling and gets you “high.”

While marijuana plants may produce CBD and CBG, they have been bred to produce high levels of THC and are therefore illegal federally

So unlike marijuana, hemp plants have virtually no THC, can be grown in all 50 states, and processed to extract cannabinoids like CBD and CBG.

In particular, CBG is not a controlled substance in the United States or internationally.

 

cannabigerol farm bill 2018

 

Since 2018, helpful compounds from hemp are available legally to everyone in the United States.

 

2018 farm bill

 

You’ll find that a lot of attention is focussing on CBG right now.

This is because access to CBG has recently increased as a result of hemp legalization and new cannabis breeding techniques are bringing down the cost to produce CBG.

Amazing, hemp extract containing CBG is starting to show up at mainstream retailers like Amazon.  Independent tests show hemp extract available on Amazon has significant quantities of CBG.

 

CBG Price And Availability

Hemp breeders are carefully working to increase the CBG content of their cannabis strains.

New strains with higher CBG yields will increase the availability of CBG and bring down the price for consumers. (6)

According to Forbes, demand for CBG has been extraordinary.

cbg for sale

CBG’s popularity is a result of its strong effects on anxiety, pain, and inflammation.

How can bring relief to you? How will CBG make you feel?

Let’s find out below.

Quick Science: CBG Chemistry

CBG is known as the “mother of all cannabinoids.”

That’s because all cannabinoids in the cannabis plant start out as CBGA (CBG’s acid form).

CBD and even THC start out as the compound CBGA before being chemically transformed within the cannabis plant.

As the plant matures, most of its CBGA is transformed into other cannabinoids like CBD and CBG prior to harvest. (7)

 

cannabinoid chemistry cbga

 

By the time this natural conversion process within the plant is over, only about 1% of the original CBGA is left.  The rest has been converted into one of the many other types of cannabinoids produced by the cannabis plant. (8)

 

hemp cannabigerol chemistry

 

Types of CBG Products 

Different types of CBG available:

  • CBG flower (CBG bud)
  • CBG tincture (extract)
  • CBG oil (extract)
  • CBG wax (concentrate)
  • CBG cream (topical)
  • CBG capsules

CBG Health Benefits In-Depth

After years of prohibition, CBG is finally available to the scientific and medical community for research.

New studies are being published and more are getting started.

While some of CBG’s benefits are known, exactly how CBG works isn’t really understood. (10)

 

cannabigerol benefit mechanism action

 

Though it has been clear for a while now that CBG has significant benefits for anxiety, pain relief, and inflammation, these effects were not studied because of hemp prohibition.

Hemp prohibition caused medical researchers to focus on more profitable, hassle-free compounds that they had better access to.

Decades of hemp prohibition made it nearly impossible for accredited universities to attain quality CBG samples and still maintain federal grant funding from federal institutions like the NIH.

That all changed with the passage of the 2018 farm bill that legalized hemp and its constituent compounds.

Below is a 2019 press release by the National Institutes of Health (NIH).

It announces a new effort to study cannabinoids like CBG for their health benefits.

cannabigerol pain relief benefit

New research is published frequently.

Stay up-to-date on recent cannabinoid medical results.

New Studies Started in 2020

Universities and NIH researchers are moving quickly to understand the health benefits of CBG.

16 new CBG medical studies were started in 2020 alone.

CBG For Pain

CBG appears to relieve pain better than THC.

There is evidence that shows CBG may be a notable muscle relaxer as well. (11)

 

cannabigerol muscle relaxer

Using CBG for pain-relief decreases the use of opiate-based painkillers that can lead to abuse.

CBG is a powerful compound for relieving pain and inflammation without causing dependency.

Unlike opioids, CBG is:

  • not habit-forming
  • not intoxicating
  • not addictive
  • not a depressive
  • not a compound that causes constipation

While many drugs exist for treating pain and muscle spasms, many have broad adverse effects profiles.

The addictive nature of opioid-based pain medications makes them a high-risk option for pain relief, often with tragic outcomes.

cbg health benefits

CBG may be a better option for us as individuals and as a nation.

CBG has minimal adverse effects, especially when compared to opioid treatments.

Interested in knowing the science behind cannabinoid pain relief? 

Check out this guide to CBD pain relief.

guide to cannabidiol benefits for pain based on 2020 medical studies

 

CBG Colon Cancer Effects

A 2014 study published in the medical journal Carcinogenesis demonstrated CBG can inhibit or slow the growth of some colon cancer tumors. (12)

 

cannabigerol cancer benefits

101,420 people were diagnosed with colon cancer in 2018 making it a leading cause of cancer in the U.S. (13)

cannabigerol colon cancer benefits

According to the study, CBG  is “a safe non-psychotropic phytocannabinoid able to block TRPM8 channels, exerts pro-apoptotic effects in CRC cells as well as chemopreventive (AOM model) and curative (xenograft model) actions in experimental models of colon cancer in Vivo.”

To be sure, CBG is far from being a treatment for cancer but it does show promise that calls for further research.

CBG For Anxiety

Medical studies show cannabigerol (CBG) has highly potent effects on hypervigilance and anxiety. In the laboratory, CBG has shown significant effects on noradrenaline and serotonin uptake within the nervous system. Noradrenaline and serotonin are believed to play important roles in causing anxiety. CBG is the only known cannabinoid to affect adrenaline uptake.

 

cannabigerol study anxiety

Is CBG Good For Anxiety?

While this research is still preliminary due to the legacy of hemp prohibition, it does suggest that CBG may have particularly fast-acting anxiety-relieving effects.

CBG vs. CBD For Anxiety

CBG has shown effects on the same nervous system receptors as CBD. Unlike CBD, CBG has shown the ability to affect noradrenaline uptake which is a natural chemical that has been associated with anxiety.

Whether CBD or CBG has a greater effect on feelings of anxiety is still up for debate from a scientific perspective.  But, from a consumer perspective, many users who have taken both CBD and CBG believe that CBG has a stronger and faster-acting anti-anxiety effect when compared to CBD.

 

cbg anxiety study

 
 

CBG For Mental Health

As the research above shows, CBG affects many of the same neurochemical receptors as CBD.  These include the CB1 and CB2 receptors as well as a key serotonin receptor.

Additionally, CBG appears to affect noradrenaline levels which may account for the reported relief that CBG has on anxiety symptoms.

Both CBG and CBD are the focus of intense medical research.  Each cannabinoid may have significant benefits for anxiety and depression.

Due to hemp prohibition, research is still underway to determine their exact benefit.

 

CBG And Terpenes For Anxiety

CBG anti-anxiety effects can be aided by matching the cannabinoid with complimentary terpenes.

Terpenes are naturally flavorful compounds also produced by hemp plants. Some anxiety-reducing terpenes are particularly good at boosting the effectiveness of CBG.

ultimate terpene guide to smell taste and health benefits

 

If anxiety is a problem for you, be sure to avoid hemp strains or tinctures with the terpene guaiol. Medical research has shown a statistical correlation between the terpene guaiol and increased feelings of anxiety.

CBG For Inflammation 

Medical studies show that cannabigerol (CBG) has unexpected neurological benefits resulting from anti-inflammatory properties. (14)

 

cannabigerol dementia alzheimers protection

 

Beyond the brain, CBG benefits gut inflammation diseases (IBS) such as ulcerative colitis and Crohn’s disease. (15)

 

cbg inflammatory bowel disease benefits

 

New research from 2018 shows CBG may help with the chronic model of multiple sclerosis and neurodegenerative diseases. (16)

 

cbg neurodegenerative multiple sclerosis therapeutic

 

CBG has significant anti-oxidant and anti-inflammatory properties.

These effects likely act as a neuroprotectant against diseases such as dementia and Alzheimer’s. (17)

 

cannabinoid dementia alzheimers benefits

 

CBG Glaucoma Benefits

Cannabinoids such as CBG and CBD can lower intraocular pressure related to glaucoma. (18)


cbg glaucoma therapy

As with several cannabinoid benefits, CBG’s mechanism of action is not fully understood. (19)

 

cannabinoid glaucoma benefits

 

It may be the case CBG is able to relax veinous pressure and increase blood circulation to the eye. (20)

 

cannabigerol ocular pressure

 

CBG can be consumed orally, topically, or as a combustion-free dab wax to decrease symptoms of high intraocular pressure.

Not familiar with dabbing or CBG concentrates? Dabbing CBG wax or rosin is  394% more efficient than smoking a flower and there’s none of the bad stuff that comes along with combustion.  See the study for a more effective way to consume cannabinoids.

CBG for Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is the result of chronic inflammation of the gastrointestinal tract.

 

Crohn’s Disease

cannabigerol inflammatory bowel disease benefits

Ulcerative Colitis

cbg inflammatory bowel disease benefits

People have been using cannabis and CBG for hundreds of years to treat inflammatory bowel disease. (21)

 

cbg gastrointestinal inflammation

 

Since the 1990s, patients have described achieving remission of inflammatory bowel disease using medical cannabis. (22)

 

medical cannabis IBD treatment

 

This research from February of 2017 describes the anti-inflammatory properties of cannabinoids.  CBG may be helpful for relieving ulcerative colitis. (23)

 

cbg colitis preventive

 

Another promising study looked at the greater endocannabinoid system’s effects on colitis.   The study noted that cannabigerol may be particularly helpful with certain models of Crohn’s Disease. (24)

 
 

cbg crohns benefits

 

The 2013 study below suggests CBG can be considered for clinical trials as a treatment for inflammatory bowel disease. (25)

cannabinoid inflammatory bowel disease therapeutic benefits

 

Interested in learning more about cannabinoid benefits for IBD?  Check out this guide based on 2020 studies.

 
 

Where Is CBG For Sale?

You can find CBG for sale online as well as in dispensaries and neighborhood CBD shops.

CBG isolate is sold online and frequently added to tinctures and oil.

 
 

CBG Entourage Effect

Blending CBG with terpenes can amplify and target the effects of both CBG and terpenes.

 

cbg booster terpenes

Terpenes interact with cannabinoids in the body to boost the effects of compounds like CBG.  (26)

This interaction is called the “entourage effect.”

 

cbg entourage effects terpenes
 

According to medical studies, consuming full spectrum CBG with the right terpenes maximizes and extends the effects of both compounds. (27)

 
 

cannabigerol terpene benefits

 

CBG Wax

CBG wax is a full-spectrum cannabinoid concentrate that is dabbed or added to a meal.

CBG wax and rosins are an especially good source of full-spectrum CBG and terpenes.

This is a video of cannabis being pressed in CBG live rosin.

Live rosin is a particularly rich source of cannabis terpenes.

https://youtu.be/0hMyCjtleIE

 

Back to table of contents ⤴

 How Does CBG Work?

“How can one compound have such varied benefits?”

The answer: CBG affects your body’s endocannabinoid system.

You can find the most in-depth information about the endocannabinoid system in this guide to CBD.

endocannabinoid properties

Both CBD and CBG interact with the endocannabinoid system in different ways.

Endocannabinoid System

Your endocannabinoid system is an important part of your nervous system.

It’s a critical regulatory system responsible for maintaining your body and mind in constant balance.

Your endocannabinoid system uses endogenous cannabinoids (cannabinoids made by your body) to send regulatory signals to different parts of your body.

Cannabinoids like CBG mimic these endogenous chemicals.

So, by consuming cannabinoids of different types (like CBG) you are affecting the signaling capacity of your nervous system and the ability of your body to remain in balance.

In general, that’s the key to why cannabinoids have such far-reaching benefits.

Roughly speaking, cannabinoids give you the power to adjust your body’s natural regulatory system.

 

anxiety emotional balance

 

Your endocannabinoid system has far-reaching responsibilities.

It regulates:

  • anxiety
  • immune system response
  • fertility
  • mood
  • appetite
  • pain sensation
  • memory (formation and destruction)
  • sleep
  • muscle recovery
  • stress response
  • inflammation

…and that’s just some of what we know about. (28)

The endocannabinoid system was discovered in 1992.

It maintains the good health of your mind and body. (29)

 

fertility inflammation pain

 

It has been said that 95% of doctors were not taught about the endocannabinoid system while in medical school.

Unfortunately, it is still poorly understood today by most general practitioners.

It’s up to you to educate yourself about the effects of your endocannabinoid system (ECS).

Knowing about your ECS will put you in more control of your own health and how you feel.

Phytocannabinoids

As we just learned, the endocannabinoid system (ECS) is part of your body’s nervous system.

It is located in your brain, spine, and throughout your body. (30)

 

natural homeostasis systems

 

Unfortunately, the endocannabinoid system is still poorly understood by medical science. (31)

 

endocannabinoid system functioning

 

Though relatively new, it is known that the endocannabinoid system (ECS) has a critical role in maintaining good health.

Your ECS naturally uses cannabinoids as a way of keeping different subsystems in your body in order.

Phytocannabinoids (plant cannabinoids) like CBG work because they mimic the endocannabinoids naturally created by your body. (32)

 

cannabigerol endocannabinoid benefits

 

In fact, phytocannabinoids like CBG and CBN are so similar to the endogenous cannabinoids created by your endocannabinoid system that your body reacts to phytocannabinoids as if it made them itself. (33)

 

cannabigerol health effects

 

That’s the secret to the health benefits of CBG and CBD–they act just like the regulatory chemicals your body all ready makes.

That’s why they’re so powerful and effective at affecting your health and how you feel.

So the answer to the question “how can one compound have such varied health benefits?” is relatively simple after all.

CBG has such varying effects because it amplifies how one of your vital regulatory systems sends messages (signals) to subsystems throughout your body.

In doing so, CBG affects the functioning of multiple regulatory systems throughout the body.

 

Back to table of contents ⤴

CBG Side Effects

CBG is generally well-tolerated and adverse effects are thought to be minimal.

CBG Adverse Effects Department of Health 

Some consumers report limited sensations of tiredness and drowsiness with a loss of appetite.

As with any cannabinoid, you may have reactions that are a result of your body’s unique chemistry.

This is completely natural.

Follow the manufacturer’s dosage recommendations and start off slowly to see how your CBG makes you feel.

Increase or decrease your CBG dosage as you feel comfortable and stop taking CBG if you start to exhibit adverse effects.

CBG Dosage

Check out this video about how to find the right CBD dosage for you.  The same principles apply to finding your best CBG dosage.

 

References

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